Searchable abstracts of presentations at key conferences in endocrinology

ea0021p239 | Neuroendocrinology and behaviour | SFEBES2009

Alarin stimulates food intake and the hypothalamo-pituitary–gonadal axis in male rats

Boughton Charlotte , Patterson Michael , Bewick Gavin , Tadross John , Gardiner James , Chaudery Faizan , Hunter George , Ghatei Mohammad , Bloom Stephen , Murphy Kevin

Alarin is the most recently discovered member of the galanin peptide family, and is encoded by a splice variant of galanin-like peptide (GALP) mRNA. Galanin and GALP are known to regulate energy homeostasis and reproduction. Galanin is thought to mediate its effects via the three-galanin receptors. GALP also binds to these known galanin receptors, but evidence suggests that it may also act via an as yet unknown GALP specific receptor. The role of alarin in energy homeostasis a...